Coll-os® – Smart Collagen Membrane
What is Coll-os®?
Coll-os® is a next-generation collagen-based membrane engineered to support effective and natural tissue regeneration in dental surgeries. Designed for maximum biocompatibility and versatility, Coll-os® is made from over 95% pure Type-I bovine collagen, closely mimicking the structure of the body’s natural extracellular matrix. This unique composition makes Coll-os® an ideal choice for procedures involving soft tissue healing, socket preservation, and periodontal regeneration.
As a bioresorbable membrane, Coll-os® safely degrades in the body over time, eliminating the need for secondary surgery and allowing for seamless tissue integration. Whether used alone or in combination with a bone graft such as Xenobone®, Coll-os® elevates the standard of care in guided tissue regeneration (GTR) and guided bone regeneration (GBR) procedures.
Key Features of Coll-os®
High-Purity Type-I Collagen
Coll-os® contains over 95% purified Type-I collagen, ensuring excellent biocompatibility and safe performance in soft tissue environments.
Natural Integration
Its structure closely replicates the extracellular matrix, allowing for smooth integration and active participation in the healing process without triggering inflammation or rejection.
Bioresorbable Composition
Coll-os® naturally resorbs over time, eliminating the need for surgical removal. The membrane safely supports healing and disappears once its role is fulfilled.
Dual-Sided Design
Thanks to its innovative double-layer structure, Coll-os® adapts easily to different anatomical areas, offering better handling and stability during placement.
Suture-Free Convenience
In many cases, Coll-os® can be used without sutures, reducing procedure time and simplifying post-operative care.
Indications for Use
Coll-os® is suitable for a variety of dental regenerative procedures, including:
Socket Preservation after tooth extraction
Periodontal Regeneration for treating intrabony defects and furcations
Gingival Recession Treatment
Bone Grafting Support in guided bone regeneration
Peri-implant Tissue Support
Its versatility makes it a preferred membrane for both simple and complex cases requiring barrier protection and soft tissue regeneration.
Benefits for Patients
Accelerated Healing with minimal post-operative discomfort
Natural Tissue Restoration without foreign body sensation
No Second Surgery due to complete bioresorption
Improved Aesthetic Results thanks to healthier soft tissue regeneration
Benefits for Clinicians
Easy Handling and Placement due to dual-surfaced design
Flexible Application in a wide range of procedures
Reduced Chair Time with suture-free options
Safe, Consistent Results backed by cleanroom manufacturing and strict quality standards
Technical Specifications
Coll-os® is available in various membrane sizes to fit specific surgical needs:
1.25 x 2.5 cm
1.5 x 2 cm
2 x 3 cm
2.5 x 2.5 cm
Each membrane is individually packaged and sterilized to ensure safety and ease of use.
Frequently Asked Questions (FAQs)
1. What makes Coll-os® different from synthetic membranes?
Unlike synthetic alternatives, Coll-os® is derived from natural collagen and offers superior biocompatibility, easy handling, and predictable resorption without the risks associated with synthetic polymers.
2. Can Coll-os® be used without sutures?
Yes. In many cases, Coll-os® can be placed securely without sutures, thanks to its adaptable structure and high adherence to soft tissue.
3. Is Coll-os® compatible with bone graft materials?
Absolutely. Coll-os® is often used in combination with bone grafts like Xenobone® in GBR procedures, offering a complete regenerative solution.
4. How long does Coll-os® stay in the body?
Coll-os® gradually resorbs over several weeks, depending on the site and individual healing response. It supports the healing process and naturally disappears as the tissue regenerates.
5. Does it require special storage conditions?
No. Coll-os® is shelf-stable and should be stored in a cool, dry place. No refrigeration is required.
Backed by DESU’s Vision for Regenerative Excellence
Coll-os® is developed by DESU, a Turkish medical innovation company specializing in neurosurgery and biomaterials. Located in the Hacettepe University Teknokent campus, DESU’s facilities include world-class cleanrooms and R&D labs where scientific knowledge meets clinical reality. Coll-os® reflects DESU’s dedication to creating globally certified, clinically effective, and safe medical solutions for improving patient outcomes and supporting dental professionals worldwide.
Coll-os® – The Smart Choice for Tissue Regeneration
Whether you’re treating periodontal defects, covering an extraction socket, or supporting peri-implant tissue, Coll-os® offers the reliability and performance you need. Its natural composition, ease of use, and clinical effectiveness make it an essential part of any modern dental regenerative toolkit.
Choose Coll-os®. Regenerate with confidence.
What is Coll-os® made of?
Coll-os® is made from over 95% pure Type-I bovine collagen, a highly biocompatible material that closely mimics the natural extracellular matrix of human tissue. This composition ensures excellent integration and promotes natural healing.
What procedures is Coll-os® used for?
Coll-os® is commonly used in a variety of dental regenerative procedures, including:
Socket preservation
Periodontal regeneration
Gingival recession coverage
Bone regeneration support
Peri-implant tissue management
Is Coll-os® bioresorbable?
Yes. Coll-os® is fully bioresorbable, meaning it naturally degrades in the body over time without requiring removal. This simplifies treatment and reduces the need for a second surgical intervention.
