What is Xenobone®?
Xenobone® is an advanced collagen-based bone graft matrix developed to meet the highest standards in modern dental and maxillofacial regenerative procedures. Composed of ultra-pure Type-I bovine collagen, Xenobone® offers a powerful blend of osteoconductive and osteoinductive properties—two essential biological mechanisms that promote accelerated and reliable bone regeneration.
Manufactured by DESU, a leading Turkish R&D-driven medical company, Xenobone® is backed by scientific innovation, strict quality control, and cleanroom production environments. It is specially designed for use in procedures such as socket preservation, sinus augmentation, periodontal defect repair, and bone augmentation.
With its clinically proven performance and versatile application range, Xenobone® helps dental professionals deliver superior outcomes while improving patient comfort and satisfaction.
Why Choose Xenobone®?
1. Ultra-Pure Type-I Collagen Composition
Xenobone® is manufactured using highly purified Type-I bovine collagen, the most biocompatible and structurally similar collagen to that of human bone. This purity minimizes immunogenic response and ensures safe integration with the patient’s own bone.
2. Osteoconductive and Osteoinductive Properties
The unique formulation of Xenobone® supports two key regenerative mechanisms:
Osteoconduction, which provides a scaffold for new bone growth
Osteoinduction, which encourages the differentiation of progenitor cells into bone-forming osteoblasts
These dual properties result in faster, more predictable healing and regeneration.
3. Microporous Architecture
Xenobone® features an innovative microporous structure that allows for optimal blood absorption, vascularization, and cellular ingrowth. This structure enhances stability and encourages natural integration with the surrounding bone tissue.
4. Sterile, Single-Use Packaging
Each unit of Xenobone® is individually sterilized to eliminate the risk of contamination and ensure maximum safety during surgical procedures. This also improves handling convenience and clinical efficiency.
5. Flexible Volume Options
To meet the diverse needs of dental professionals, Xenobone® is available in 1cc, 2cc, 5cc, and 10cc sizes. The 5cc pack, in particular, offers an excellent balance between volume and cost-efficiency for mid- to large-scale procedures.
Clinical Applications of Xenobone®
Xenobone® is suitable for a wide range of clinical situations, including but not limited to:
Socket Preservation: Maintains ridge dimensions after tooth extraction and prepares the site for future implant placement.
Periodontal Defects: Supports bone fill in intrabony and furcation defects.
Sinus Lifts: Facilitates maxillary sinus floor elevation with predictable bone formation.
Horizontal and Vertical Bone Augmentation: Reconstructs lost bone volume in edentulous or atrophic sites.
Peri-implant Defect Management: Promotes integration and long-term success of dental implants.
These use cases demonstrate Xenobone®’s flexibility in routine as well as advanced dental surgical protocols.
Benefits for Patients
Faster Recovery: Accelerated bone healing reduces post-operative discomfort and downtime.
Improved Long-Term Outcomes: Enhanced integration results in stronger, more stable bone support for implants and prosthetics.
Reduced Risk of Complications: The high purity and biocompatibility of collagen help avoid inflammation or graft rejection.
Minimally Invasive Experience: Packaged for single use, Xenobone® supports clean, safe, and efficient procedures.
Benefits for Dental Professionals
Reliable Clinical Performance: Consistent results across diverse case types.
Easy Handling: Granule formulation allows for precise placement and adaptation to defect morphology.
Time-Saving: Pre-packaged and sterilized, ready for immediate use in surgery.
Adaptable Inventory: Multiple sizes ensure the right graft volume is always available without waste.
Product Variants and Technical Specifications
Xenobone® is offered in a range of granule sizes to suit varying clinical demands:
0.7–1.5 mm
2–3 mm
4–5 mm
6–7 mm
Each granule size is available in 1cc, 2cc, 5cc, and 10cc vials, all of which are packaged under sterile conditions. The packaging is designed for easy opening and application during surgical procedures.
Backed by Research, Driven by Innovation
Xenobone® is manufactured by DESU in its certified cleanroom facilities (ISO Class 10,000 and 1,000) in Ankara, Turkey. These advanced production standards ensure that every batch meets stringent quality and safety criteria. All DESU products are developed in close collaboration with clinicians, researchers, and biomedical engineers to address real-world challenges in regenerative dentistry.
DESU is committed to transforming high-level scientific research into tangible clinical solutions that enhance human health and improve treatment outcomes worldwide.
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Is Xenobone® suitable for all patients?
Yes. Thanks to its high biocompatibility and purity, Xenobone® is well-tolerated by most patients. However, clinicians should always evaluate patient history and allergies before application.
What is Xenobone® made of?
Xenobone® is composed of ultra-pure Type-I bovine collagen, which is highly biocompatible and structurally similar to human collagen. This material supports rapid bone regeneration while minimizing the risk of immune response.
In which clinical cases can Xenobone® be used?
Xenobone® is ideal for a wide range of dental and maxillofacial procedures, including:
Socket preservation after tooth extraction
Sinus lifts (open or closed technique)
Periodontal defect treatment
Horizontal and vertical ridge augmentation
Peri-implant bone regeneration
Is Xenobone® safe for all patients?
Yes. Xenobone® has been carefully formulated and processed to ensure maximum purity and safety. However, patients with known allergies to bovine-derived materials should be evaluated carefully before use.
What is the expected healing time after using Xenobone®?
Healing time varies based on the procedure and patient-specific factors, but new bone formation is typically observed within 3 to 6 months. Xenobone®’s osteoconductive and osteoinductive properties promote early integration and predictable outcomes.
Does Xenobone® require a barrier membrane?
In some procedures, especially where soft tissue invasion is a concern, it is highly recommended to use a resorbable membrane such as Coll-os® in conjunction with Xenobone® to optimize guided bone regeneration (GBR).
What granule sizes and volumes are available?
Xenobone® comes in the following granule sizes:
0.7–1.5 mm
2–3 mm
4–5 mm
6–7 mm
Each granule size is available in volumes of 1cc, 2cc, 5cc, and 10cc, offering flexibility for procedures of all scales.